drugset / Trial / NCT01810952
The Management of Glucocorticoid-Induced Hyperglycemia in Hospitalized Patients
RandomizedParallel-groupOpen-labelTreatment
Summary
The investigators hypothesize that includes patient weight and glucocorticoid dose can be used to safely initiate insulin treatment in diabetic/hyperglycemic patients who are to be treated with pharmacological doses of glucocorticoids.
Timeline
- Start
- 2010-09
- Primary completion
- 2013-09
- Completion
- 2013-09
Publications
- Background Clore JN, Thurby-Hay L. Glucocorticoid-induced hyperglycemia. Endocr Pract. 2009 Jul-Aug;15(5):469-74. doi: 10.4158/EP08331.RAR.
- Background Moghissi ES, Korytkowski MT, DiNardo M, Einhorn D, Hellman R, Hirsch IB, Inzucchi SE, Ismail-Beigi F, Kirkman MS, Umpierrez GE; American Association of Clinical Endocrinologists; American Diabetes Association. American Association of Clinical Endocrinologists and American Diabetes Association consensus statement on inpatient glycemic control. Diabetes Care. 2009 Jun;32(6):1119-31. doi: 10.2337/dc09-9029. Epub 2009 May 8. No abstract available.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Insulin | Protein / enzyme biologic | 0.1 iu/kg | — |
| Subject | Insulin | Protein / enzyme biologic | 0.4 iu/kg | — |
| Background | Insulin Lispro | Protein / enzyme biologic | 0.1 iu/kg | — |
| Background | Insulin Lispro | Protein / enzyme biologic | 0.2 iu/kg | — |
| Background | Insulin Lispro | Protein / enzyme biologic | 0.4 iu/kg | — |
| Background | insulin glargine | Protein / enzyme biologic | 0.2 iu/kg | — |