drugset / Trial / NCT01824823
Afatinib After Chemoradiation and Surgery in Treating Patients With Stage III-IV Squamous Cell Carcinoma of the Head and Neck at High-Risk of Recurrence
Phase 2
Terminated
3 enrolled
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This randomized phase II trial studies how well giving afatinib after chemoradiation and surgery works in treating patients with stage III-IV squamous cell carcinoma of the head and neck at high-risk of recurrence. Afatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Timeline
- Start
- 2014-06-30
- Primary completion
- 2015-12-13
- Completion
- 2020-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Afatinib | Small molecule | — | Oral |