drugset / Trial / NCT01826838
Study of Dasatinib, Androgen Deprivation Therapy and Radiation
NaSingle-groupOpen-labelTreatment
Summary
Radiation and androgen deprivation is a common modality for patients with localized prostate cancer. Unfortunately for patients with intermediate to high risk prostate cancer incomplete tumor eradication and subsequent relapse occurs in 50-75% of patients. The Src pathway appears to be integral to the pathobiology of prostate cancer and may be fundamental to radioresistance.
Timeline
- Start
- 2013-01
- Primary completion
- 2013-04
- Completion
- 2013-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | dasatinib anhydrous | Small molecule | 50 mg | — |
| Subject | dasatinib anhydrous | Small molecule | 70 mg | — |
| Subject | dasatinib anhydrous | Small molecule | 100 mg | — |