drugset / Trial / NCT01827930

Phase III Trial Evaluating the Effectiveness of a Dose Adjustment of Imatinib Mesylate on the Molecular Response

NCT01827930

Phase 3 Terminated 68 enrolled Institut Bergonié Novartis · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

The Imatinib Mesylate at a dose of 400 mg / day is the standard treatment for patients with CML-CP. Recent studies show that the quality of response rate (complete cytogenetic response and major molecular response rate) is dependent on the residual plasma Imatinib.

Timeline

Start
2009-07
Primary completion
2017-01-01
Completion
2017-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Imatinib Small molecule 400 mg Oral
Subject Imatinib Small molecule 600 mg Oral