Safety Study of ChAdOx1 85A Vaccination With and Without MVA85A Boost in Healthy Adults

Phase 1 Completed 42 enrolled University of Oxford University of Birmingham · collab

RandomizedParallel-groupOpen-labelPrevention

Summary

This is a Phase I trial to evaluate the safety and immunogenicity of a ChAdOx1 85A vaccination with and without MVA85A boost in healthy BCG vaccinated adults.

Timeline

Start: 2013-07
Primary completion: 2016-04
Completion: 2016-04

Publications

Crisan-Dabija R, Grigorescu C, Pavel CA, Artene B, Popa IV, Cernomaz A, Burlacu A. Tuberculosis and COVID-19: Lessons from the Past Viral Outbreaks and Possible Future Outcomes. Can Respir J. 2020 Sep 5;2020:1401053. doi: 10.1155/2020/1401053. eCollection 2020.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	ChAdOx1 85A	Vaccine	5e+09 vg	Intramuscular
Subject	ChAdOx1 85A	Vaccine	2.5e+10 vg	Intramuscular
Subject	MVA85A	Vaccine	1e+08 unknown	Intramuscular

Safety Study of ChAdOx1 85A Vaccination With and Without MVA85A Boost in Healthy Adults

Summary

Timeline

Publications

Drugs

Indications