drugset / Trial / NCT01831076

Preoperative Hormone Therapy for Postmenopausal Women With ER+ Clinical Stage T2-4 Tumors

NCT01831076

Phase 2 Completed 36 enrolled University of Colorado, Denver
RandomizedParallel-groupOpen-labelTreatment

Summary

This phase II trial studies how well exemestane before surgery works in treating postmenopausal patients with newly diagnosed estrogen receptor positive stage II-III breast cancer. Estrogen can cause the growth of breast cancer cells. Hormone therapy using exemestane may fight breast cancer by blocking the use of estrogen by the tumor cells.

Timeline

Start
2002-04
Primary completion
2013-02
Completion
2022-01-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Exemestane Small molecule 25 mg Oral
Subject Tamoxifen Small molecule 20 mg Oral