drugset / Trial / NCT01832753
Treatment Trial of Subclinical Hypothyroidism in Down Syndrome
Completed
12 enrolled
Children's Hospital of Philadelphia
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this research study is to learn about the effects of treating subclinical hypothyroidism (SCH) with thyroid hormone replacement in children and adolescents with Down syndrome (DS). We hypothesize that treatment of SCH with thyroid hormone replacement will improve cardiometabolic health and quality of life.
Timeline
- Start
- 2013-01
- Primary completion
- 2017-10-18
- Completion
- 2017-10-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Levothyroxine | Other / unclassified | 0.5 ug/kg | — |
| Comparator | Levothyroxine | Other / unclassified | 1 ug/kg | — |