drugset / Trial / NCT01833078

Ghrelin Repeated Dose Study

NCT01833078

Phase 2 Completed 5 enrolled University of Pennsylvania
NaSingle-groupOpen-labelTreatment

Summary

Frailty is a geriatric syndrome leading to physical deterioration including muscle wasting (sarcopenia) and unintentional weight loss. There are currently no approved therapies for frailty. Ghrelin is a hormone produced by the stomach that stimulates appetite centers in the brain. The investigators already know that a single dose of Ghrelin improves food intake immediately after the dose in frail older people. In this study, the investigators are trying to find out if repeated daily doses of ghrelin will help frail older people improve food intake for multiple days in a row.

Timeline

Start
2013-02
Primary completion
2013-06
Completion
2013-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Ghrelin Peptide 7.5 ug/kg Subcutaneous

Indications

No indication recorded.