drugset / Trial / NCT01833455

Premature Ventricular Contractions (PVCs) and Blood Pressure Control

NCT01833455

Phase 2 Terminated 8 enrolled University of Wisconsin, Madison
RandomizedCrossoverQuadruple-blindBasic science

Summary

The purpose of this study is to determine if reduction in premature ventricular contraction (PVC) burden results in a decrease in blood pressure, sympathetic outflow, plasma catecholamines and an improvement in baroreflex gain. Flecainide will be used for PVC suppression in a randomized, double-blinded, crossover fashion.

Timeline

Start
2013-02
Primary completion
2016-06
Completion
2016-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator flecainide Small molecule