Method of Endogenous TSH Stimulation in the Follow-up of Differentiated Thyroid Cancer

Summary

The treatment of differentiated thyroid cancer (DCT) includes surgery followed by radioiodine treatment. In the follow-up of patients it is necessary to induce TSH elevation to test for cancer recurrence. One of the options is to stop L-thyroxin replacement for several weeks. Current pilot study aims to induce the necessary TSH elevation by decreasing the L-thyroxin dose. The main hypothesis is that necessary TSH stimulation will be achieved during 4-6 weeks in majority of patients.

Timeline

Start

2013-04

Primary completion

2014-02

Completion

2014-02

Drugs

Indications