Carfilzomib and Melphalan Before Stem Cell Transplant in Treating Patients With Multiple Myeloma

Summary

This phase I/II trial studies the side effects and best dose of carfilzomib when given together with melphalan and to see how well they work in treating patients with multiple myeloma before stem cell transplant. Carfilzomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as melphalan, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving carfilzomib together with melphalan may kill more cancer cells.

Timeline

Start

2013-06-04

Primary completion

2017-10-11

Completion

2019-10-28

Drugs

Indications