drugset / Trial / NCT01852370

Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases

NCT01852370

Phase 1/2 Enrolling by invitation 16 enrolled Paul Szabolcs
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine whether bilateral orthotopic lung transplantation (BOLT) followed by cadaveric partially-matched hematopoietic stem cell transplantation (HSCT) is safe and effective for patients aged 5-45 years with primary immunodeficiency (PID) and end-stage lung disease.

Timeline

Start
2013-06-20
Primary completion
2026-11
Completion
2027-11

Drugs

EvaluationDrugModalityDoseRoute
Subject allogeneic hematopoietic stem cells Cell therapy