Iron Supplementation for Acute Anemia After Postbariatric Abdominoplasty

Summary

The purpose of this study is to determine whether intravenous or oral iron are effective in the treatment of postoperative anemia and iron deficiency in patients submitted in postbariatric abdominoplasty.

Timeline

Start

2014-04

Primary completion

2016-04

Completion

2016-06

Outcome

Missed primary endpoint

paper Although superiority of intravenous iron was not shown PMID 29958570 ↗

paper The minimum clinically relevant difference in concentrations was not reached. PMID 29958570 ↗

Publications

• Montano-Pedroso JC, Bueno Garcia E, Alcantara Rodrigues de Moraes M, Francescato Veiga D, Masako Ferreira L. Intravenous iron sucrose versus oral iron administration for the postoperative treatment of post-bariatric abdominoplasty anaemia: an open-label, randomised, superiority trial in Brazil. Lancet Haematol. 2018 Jul;5(7):e310-e320. doi: 10.1016/S2352-3026(18)30071-1.
• Montano-Pedroso JC, Garcia EB, Novo NF, Veiga DF, Ferreira LM. Postoperative intravenously administered iron sucrose versus postoperative orally administered iron to treat post-bariatric abdominoplasty anaemia (ISAPA): the study protocol for a randomised controlled trial. Trials. 2016 Apr 12;17:196. doi: 10.1186/s13063-016-1300-x.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Iron III Hydroxide Polymaltose Complex	Unknown	100 mg	Oral
Subject	Iron sucrose	Unknown	200 mg	Intravenous

Indications