drugset / Trial / NCT01861223

Afatinib Plus Nimotuzumb for NSCLC

NCT01861223

Phase 1/2 Unknown 50 enrolled Samsung Medical Center
NaSingle-groupOpen-labelTreatment

Summary

To find the optimal dose of afatinib and nimotuzumab in patients who acquired resistance to gefitinib or erlotinib.

Timeline

Start
2013-05
Primary completion
2015-05
Completion
2016-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Afatinib Small molecule 30 mg
Subject Afatinib Small molecule 40 mg
Subject Nimotuzumab Monoclonal antibody 100 mg
Subject Nimotuzumab Monoclonal antibody 200 mg