drugset / Trial / NCT01862458

Empyema Treated With tPA & DNAse

NCT01862458

RandomizedParallel-groupTriple-blindTreatment

Summary

The objective of this study is to scientifically evaluate a new substrate for fibrinolysis compared to our standard tPA. The hypothesis, driven by a recent prospective trial, is that tPA may benefit from the addition of DNAse. The primary outcome variable between the two techniques will be length of hospitalization after initiation of treatment.

Timeline

Start
2016-01
Primary completion
2016-01
Completion
2016-01

Drugs

EvaluationDrugModalityDoseRoute
Subject dornase Unknown
Comparator Alteplase Protein / enzyme biologic

Indications