drugset / Trial / NCT01862458
Empyema Treated With tPA & DNAse
RandomizedParallel-groupTriple-blindTreatment
Summary
The objective of this study is to scientifically evaluate a new substrate for fibrinolysis compared to our standard tPA. The hypothesis, driven by a recent prospective trial, is that tPA may benefit from the addition of DNAse. The primary outcome variable between the two techniques will be length of hospitalization after initiation of treatment.
Timeline
- Start
- 2016-01
- Primary completion
- 2016-01
- Completion
- 2016-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | dornase | Unknown | — | — |
| Comparator | Alteplase | Protein / enzyme biologic | — | — |