drugset / Trial / NCT01864005

A Phase IV Study of the Onset and Maintenance of the Antiplatelet Effect of Ticagrelor Compared With Clopidogrel in Chinese Patients With ACS

NCT01864005 ↗

Phase 4 Completed 60 enrolled AstraZeneca
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to test the hypothesis that the onset of the antiplatelet effect of ticagrelor is more rapid and greater than clopidogrel in Chinese patients with ACS.

Timeline

Start
2013-05
Primary completion
2014-03
Completion
2014-03

Outcome

Met primary endpoint

registry analysis (superiority or other test); Ticagrelor vs Clopidogrel; p = 0.0021; Wilcoxon (Mann-Whitney); note: not adjusted for multiple comparisons. NCT01864005 ↗

Drugs

EvaluationDrugModalityDoseRoute
Comparator Clopidogrel Small molecule 75 mg Oral
Subject Ticagrelor Small molecule 90 mg Oral