drugset / Trial / NCT01864005
A Phase IV Study of the Onset and Maintenance of the Antiplatelet Effect of Ticagrelor Compared With Clopidogrel in Chinese Patients With ACS
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to test the hypothesis that the onset of the antiplatelet effect of ticagrelor is more rapid and greater than clopidogrel in Chinese patients with ACS.
Timeline
- Start
- 2013-05
- Primary completion
- 2014-03
- Completion
- 2014-03
Outcome
Met primary endpoint
registry analysis (superiority or other test); Ticagrelor vs Clopidogrel; p = 0.0021; Wilcoxon (Mann-Whitney); note: not adjusted for multiple comparisons. NCT01864005 ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Clopidogrel | Small molecule | 75 mg | Oral |
| Subject | Ticagrelor | Small molecule | 90 mg | Oral |