Amiloride Hydrochlorothiazide as Treatment of Acute Inflammation of the Optic Nerve

Summary

Following acute inflammation of the optic nerve region, as commonly seen in multiple sclerosis patients, the optic nerve often undergoes atrophy, thus representing permanent damage. Data from animal studies suggest that amiloride may prevent this process. The aim of this study is to assess a potential neuroprotective effect of amiloride in acute autoimmune inflammation of the optic nerve region.

Timeline

Start

2014-03

Primary completion

2016-04

Completion

2016-04

Drugs

Indications