drugset / Trial / NCT01883102

The Effect of Ablation of Epidermal Nerve Fibers Using Capsaicin Cream

NCT01883102

Phase 1 Completed 1 enrolled Mayo Clinic
Non-randomizedFactorialDouble-blindSupportive care

Summary

This is a study of epidermal (the outer most layer) nerve fibers (ENFs) in the skin of the body; counts of which are used to determine a disease of nerves called "small nerve fiber neuropathy." Capsaicin is approved by the Food and Drug Administration (FDA) for pain relief. Since 0.1% capsaicin is known to cause ablation (removal) of ENFs, this study will test whether such ablation results in relief of spontaneous pain, touch, or heat-pain.

Timeline

Start
2013-06
Primary completion
2013-06
Completion
2013-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Capsaicin Small molecule 0.1 % Topical

Indications

No indication recorded.