drugset / Trial / NCT01884636
A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Methotrexate
Phase 1
Completed
24 enrolled
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd · collab
NaSingle-groupOpen-label
Summary
The purpose of this study is to assess the effect of multiple doses of isavuconazole on the pharmacokinetics of a single dose of methotrexate. Safety and tolerability of isavuconazole will be assessed alone and in combination with methotrexate.
Timeline
- Start
- 2013-02
- Primary completion
- 2013-03
- Completion
- 2013-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Isavuconazole | Small molecule | — | Oral |
| Subject | Methotrexate | Small molecule | — | Oral |