drugset / Trial / NCT01886976

Treatment of Chemotherapy Refractory Multiple Myeloma by CART-138

NCT01886976 ↗

Phase 1/2 Unknown 10 enrolled Chinese PLA General Hospital
NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: Placing a tumor antigen chimeric receptor that has been created in the laboratory into patient autologous or donor-derived T cells may make the body build immune response to kill cancer cells. PURPOSE: This clinical trial is to study genetically engineered lymphocyte therapy in treating patients with CD138 positive multiple myeloma that is relapsed (after stem cell transplantation or intensive chemotherapy) or refractory to further chemotherapy.

Timeline

Start
2013-06
Primary completion
2016-06
Completion
2016-06

Drugs

EvaluationDrugModalityDoseRoute
Subject CART-138 cells Cell therapy — —

Indications