drugset / Trial / NCT01887223
Transconjunctival Needling Revision Versus Medical Treatment
RandomizedParallel-groupOpen-labelTreatment
Summary
When the glaucoma filtering surgery failures (intraocular pressure rises again), the options is start to use the hypotensive eye drops again (medical treatment). However, in some cases (encapsulated blebs), there is a simple surgical revision that can revival the primary failure surgery. It calls transconjunctival needling revision. In this study, the investigators compare the efficacy of this revision versus medical treatment in 12-month follow up in eyes with encapsulated blebs.
Timeline
- Start
- 2010-05
- Primary completion
- 2011-06
- Completion
- 2011-06
Publications
- Results Costa VP, Correa MM, Kara-Jose N. Needling versus medical treatment in encapsulated blebs. A randomized, prospective study. Ophthalmology. 1997 Aug;104(8):1215-20. doi: 10.1016/s0161-6420(97)30155-9.
- Suzuki R, Susanna R Jr. Early transconjunctival needling revision with 5-fluorouracil versus medical treatment in encapsulated blebs: a 12-month prospective study. Clinics (Sao Paulo). 2013 Oct;68(10):1376-9. doi: 10.6061/clinics/2013(10)14.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Brimonidine | Small molecule | — | — |
| Comparator | Dorzolamide | Small molecule | — | — |
| Comparator | Latanoprost | Small molecule | — | — |
| Comparator | Timolol | Other / unclassified | 0.5 % | — |