drugset / Trial / NCT01887535

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-54861911 in Healthy Elderly Participants

NCT01887535

Phase 1 Completed 70 enrolled Janssen Research & Development, LLC
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple-ascending dose JNJ-54861911 which is currently being developed for the treatment of Alzheimer's disease.

Timeline

Start
2013-05
Primary completion
2013-12
Completion
2013-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Atabecestat Small molecule 3 mg Oral
Subject Atabecestat Small molecule 10 mg Oral
Subject Atabecestat Small molecule 25 mg Oral
Subject Atabecestat Small molecule 30 mg Oral
Subject Atabecestat Small molecule 80 mg Oral

Indications

No indication recorded.