drugset / Trial / NCT01888965

Maintenance Dovitinib for Colorectal and Pancreas Cancer

NCT01888965

Phase 2 Terminated 9 enrolled Georgetown University Novartis · collab
NaSingle-groupOpen-labelTreatment

Summary

This study is for patients with stage 4 colon cancer who have had initial chemotherapy or had surgery to remove metastases and patients with pancreas cancer, which has been surgically removed and are receiving adjuvant chemotherapy or is locally advanced and have already received chemotherapy and radiation. The purpose of this study is to determine the effects of oral dovitinib in patients with advanced stage colorectal and pancreas. Effects include biomarker changes, progression-free survival and safety. Dovitinib will be taken by mouth for 5 days out of every week for up to 2 years.

Timeline

Start
2013-10
Primary completion
2014-08
Completion
2014-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Dovitinib Small molecule 300 mg Oral
Subject Dovitinib Small molecule 400 mg Oral
Subject Dovitinib Small molecule 500 mg Oral