drugset / Trial / NCT01893658

Xolair (Omalizumab) for Treatment of Drug-induced Acute Tubulointerstitial Nephritis (AIN)

NCT01893658

RandomizedParallel-groupOpen-labelTreatment

Summary

The investigators goal is to evaluate the role of XOLAIR® in treatment of Acute Tubulointerstitial Nephritis (AIN) with the goal of shortening the duration and dose of prednisone for treatment of drug-induced AIN. Currently there is no good treatment for drug-induced AIN. Prednisone is the standard treatment but is associated with many side-effects when used long-term and at high doses.

Timeline

Start
2018-06-01
Primary completion
2018-09-28
Completion
2018-09-28

Drugs

EvaluationDrugModalityDoseRoute
Comparator Omalizumab Monoclonal antibody 375 mg Subcutaneous
Comparator Prednisone Other / unclassified 60 mg