drugset / Trial / NCT01893658
Xolair (Omalizumab) for Treatment of Drug-induced Acute Tubulointerstitial Nephritis (AIN)
RandomizedParallel-groupOpen-labelTreatment
Summary
The investigators goal is to evaluate the role of XOLAIR® in treatment of Acute Tubulointerstitial Nephritis (AIN) with the goal of shortening the duration and dose of prednisone for treatment of drug-induced AIN. Currently there is no good treatment for drug-induced AIN. Prednisone is the standard treatment but is associated with many side-effects when used long-term and at high doses.
Timeline
- Start
- 2018-06-01
- Primary completion
- 2018-09-28
- Completion
- 2018-09-28
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Omalizumab | Monoclonal antibody | 375 mg | Subcutaneous |
| Comparator | Prednisone | Other / unclassified | 60 mg | — |