drugset / Trial / NCT01897415

Autologous Redirected RNA Meso CAR T Cells for Pancreatic Cancer

NCT01897415 ↗

Phase 1 Completed 16 enrolled University of Pennsylvania
NaSingle-groupOpen-labelTreatment

Summary

This is a Phase I safety and feasibility study. Subjects will be enrolled serially. For subject safety, the preceding subject must have completed one cycle of therapy (28 days) before the next subject can be treated. Subjects will be treated with i.v. administration of 1 to 3e8 per meter squared RNA CAR T cells three times weekly (M-W-F) for three weeks.

Timeline

Start
2013-07
Primary completion
2015-12
Completion
2017-03

Drugs

EvaluationDrugModalityDoseRoute
Subject SS-1 Cell therapy 1e+08 unknown Intravenous
Subject SS-1 Cell therapy 3e+08 unknown Intravenous