drugset / Trial / NCT01898611

Ghrelin Plus Strength Training in Frail Elderly Study

NCT01898611

Phase 2 Completed 16 enrolled University of Pennsylvania
RandomizedParallel-groupQuadruple-blindOther

Summary

Frailty is a geriatric syndrome leading to physical deterioration including muscle wasting (sarcopenia) and unintentional weight loss. There are currently no approved therapies for frailty. Ghrelin is a hormone produced by the stomach that stimulates appetite centers in the brain. The investigators already know that a single dose of Ghrelin improves food intake immediately after the dose in frail older people. In addition, exercise programs have been shown to improve strength and function in older people. In this study, the investigators are trying to find out if a joint intervention of ghrelin and resistance training will improve walking, balance and leg strength in frail elderly people.

Timeline

Start
2013-07-01
Primary completion
2016-08-31
Completion
2016-08-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ghrelin Peptide 7.5 ug/kg Subcutaneous

Indications

No indication recorded.