drugset / Trial / NCT01902550
A Crossover Study to Evaluate the Effect of JNJ-54452840 on Pharmacodynamics of Metoprolol Tartrate Immediate-Release in Healthy Participants
RandomizedCrossoverDouble-blindTreatment
Summary
The purpose of this study is to evaluate effect of co-administration of JNJ-54452840 and metoprolol tartrate immediate-release (metoprolol IR) compared to metoprolol IR alone on the exercise heart rate and blood pressure measured at the end of each 3-minute exercise test in healthy participants.
Timeline
- Start
- 2013-07
- Primary completion
- 2013-10
- Completion
- 2014-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | MIBENRATIDE | Protein / enzyme biologic | 240 mg | Intravenous |
| Subject | Metoprolol | Other / unclassified | 100 mg | Oral |
Indications
No indication recorded.