drugset / Trial / NCT01906528
Sex-related Differences in the Response to the Muscle Relaxant Drug Mivacurium
Phase 1
Completed
20 enrolled
University of California, San Francisco
Oslo University Hospital · collab
NaSingle-groupOpen-labelTreatment
Summary
Muscle relaxants are drugs providing muscle relaxation during surgical treatment. Previous studies have shown that males and females respond differently to this kind of drug. Our hypothesis is that males are more sensitive to the effect of Mivacurium (a muscle relaxant) than females, meaning that males need a lower blood concentration of the drug than females in order to obtain a given effect.
Timeline
- Start
- 2013-03
- Primary completion
- 2013-07
- Completion
- 2013-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mivacurium | Small molecule | 1 ug/kg | Intravenous |
| Subject | Mivacurium | Small molecule | 3 ug/kg | Intravenous |
Indications
No indication recorded.