drugset / Trial / NCT01907724
Drug-Drug Interaction Between IDX719, Simeprevir, TMC647055 and Ritonavir When Administered in Combination in Healthy Participants (MK-1894-007)
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to evaluate the potential for a PK drug-drug interaction when IDX719, simeprevir, TMC647055 and low-dose ritonavir (RTV) are administered in combination. Safety and tolerability will also be assessed.
Timeline
- Start
- 2013-05
- Primary completion
- 2013-08
- Completion
- 2013-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | RTV | Unknown | 30 mg | Oral |
| Subject | Samatasvir | Small molecule | 150 mg | Oral |
| Subject | Simeprevir | Small molecule | 75 mg | Oral |
| Subject | TMC647055 | Small molecule | 450 mg | Oral |