drugset / Trial / NCT01913106

HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer

NCT01913106

Phase 1/2 Recruiting 25 enrolled The Methodist Hospital Research Institute
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to conduct a Phase I - II clinical trial to extend preclinical studies involving in situ HSV-tk + Valacyclovir gene therapy in combination with brachytherapy for recurrent prostate cancer. This will provide a novel therapeutic approach to prostate cancer and hopefully impact on the development of metastatic disease and the control of preexisting metastasis.

Timeline

Start
2007-06
Primary completion
2018-12
Completion
2028-12

Drugs

EvaluationDrugModalityDoseRoute
Subject aglatimagene besadenovec Unknown 1 ml Other
Subject aglatimagene besadenovec Unknown 2 ml Other
Background Valacyclovir Unknown Oral

Indications