drugset / Trial / NCT01913106
HSV-tk + Valacyclovir Therapy in Combination With Brachytherapy for Recurrent Prostate Cancer
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to conduct a Phase I - II clinical trial to extend preclinical studies involving in situ HSV-tk + Valacyclovir gene therapy in combination with brachytherapy for recurrent prostate cancer. This will provide a novel therapeutic approach to prostate cancer and hopefully impact on the development of metastatic disease and the control of preexisting metastasis.
Timeline
- Start
- 2007-06
- Primary completion
- 2018-12
- Completion
- 2028-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | aglatimagene besadenovec | Unknown | 1 ml | Other |
| Subject | aglatimagene besadenovec | Unknown | 2 ml | Other |
| Background | Valacyclovir | Unknown | — | Oral |