drugset / Trial / NCT01916902

Effect of Pretreatment With Ticagrelor on Residual Thrombus After PCI in Patients Presenting With ACS in Comparison With Delayed Treatment at the Time of PCI: an OCT Study

NCT01916902

RandomizedParallel-groupSingle-blind

Summary

Subjects presenting with probable acute coronary syndromes scheduled for cardiac catheterization will be enrolled in this study. Consented subjects will be randomized to receive ticagrelor started with a loading dose immediately after enrollment versus receiving a loading dose of ticagrelor during cardiac catheterization after diagnostic angiography but prior to stenting. Optical coherence tomography (OCT) will be performed after stenting and the volume of thrombus within the new stent will be measured and compared between the groups.

Timeline

Start
2014-02
Primary completion
2015-02
Completion

Drugs

EvaluationDrugModalityDoseRoute
Comparator Ticagrelor Small molecule 180 mg