Tongxinluo Capsule in Ischemic Stroke Patients（TISS)

Summary

The purpose of this study is to assess the effects in improving life self-care ability of stroke patients after taking Tongxinluo Capsule(within 72 hours after onset) versus Placebos for 90 days.

Timeline

Start

2014-03

Primary completion

2016-10

Completion

2016-11

Outcome

Met primary endpoint

paper Patients in the Tongxinluo group had a significantly higher proportion of favorable functional outcomes at day 90 compared with those in the control group PMID 39325453 ↗

Publications

• Dong Y, Jiang K, Li Z, Zhou Y, Ju B, Min L, He Q, Fan P, Hu W, Qu H, Wu H, Pan C, Cao Y, Lou X, Zhang G, Zhang J, Hu F, Dong Q; TISS Trial Investigators. Tongxinluo and Functional Outcomes Among Patients With Acute Ischemic Stroke: A Randomized Clinical Trial. JAMA Netw Open. 2024 Sep 3;7(9):e2433463. doi: 10.1001/jamanetworkopen.2024.33463.

Drugs

Indications