drugset / Trial / NCT01919918
Muscle Afferent Feedback Effects in Patients With Heart Failure
Non-randomizedParallel-groupOpen-labelBasic science
Summary
The purpose of the study is to find out more about the mechanism by which neural feedback from the working muscle affects the development of central fatigue during exercise. Subjects with chronic heart failure (HF) and healthy subject counterparts will be tested to determine the mechanisms accounting for the premature fatigue characterizing HF patients during physical activity.
Timeline
- Start
- 2013-09
- Primary completion
- 2018-01-03
- Completion
- 2018-01-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lactate | Unknown | — | — |
| Subject | adenosine triphosphate | Small molecule | — | — |
| Subject | protons | Unknown | — | — |