drugset / Trial / NCT01921010

Benefit of Elevation of HDL-C in Women

NCT01921010

Phase 4 Completed 43 enrolled Cedars-Sinai Medical Center
RandomizedParallel-groupDouble-blindTreatment

Summary

The combination of HDL-C elevation, lowering of triglycerides and further LDL-C reduction accomplished by the addition of niacin to statin medication would improve endothelial function as compared to LDL-C reduction alone in patients with and without coronary artery disease and the combination of low HDL-C/high triglycerides. The combination of lipid lowering therapy would have beneficial effects on markers of inflammation. These benefits would be particularly evident in women.

Timeline

Start
2003-06
Primary completion
2005-06
Completion
2005-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Niacin Small molecule 1.5 g

Indications

No indication recorded.