drugset / Trial / NCT01921010
Benefit of Elevation of HDL-C in Women
RandomizedParallel-groupDouble-blindTreatment
Summary
The combination of HDL-C elevation, lowering of triglycerides and further LDL-C reduction accomplished by the addition of niacin to statin medication would improve endothelial function as compared to LDL-C reduction alone in patients with and without coronary artery disease and the combination of low HDL-C/high triglycerides. The combination of lipid lowering therapy would have beneficial effects on markers of inflammation. These benefits would be particularly evident in women.
Timeline
- Start
- 2003-06
- Primary completion
- 2005-06
- Completion
- 2005-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Niacin | Small molecule | 1.5 g | — |
Indications
No indication recorded.