Benzocaine Versus Placebo Spray for Pain Relief at Hysterosalpingogram

NCT01925469 ↗

Phase 4 Completed 30 enrolled University of Pennsylvania

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The objective of this study is to assess the utility of benzocaine spray versus a placebo spray in alleviating pain during and after hysterosalpingogram (HSG).

Timeline

Start: 2011-12
Primary completion: 2012-04
Completion: 2012-04

Outcome

Missed primary endpoint

registry analysis (superiority or other test); Benzocaine vs Saline Spray; p = 0.43; Wilcoxon (Mann-Whitney) NCT01925469 ↗

paper The use of benzocaine spray does not significantly improve pain relief during HSG nor does it hasten resolution of pain post HSG. PMID 24745839 ↗

Publications

Bachman EA, Senapati S, Sammel MD, Kalra SK. Randomized controlled trial of benzocaine versus placebo spray for pain relief at hysterosalpingogram. Reprod Biomed Online. 2014 Jun;28(6):748-52. doi: 10.1016/j.rbmo.2014.02.012. Epub 2014 Mar 4.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Benzocaine	Small molecule	14 %	—

Indications

No indication recorded.