drugset / Trial / NCT01925638
Effect of Ketoconazole on the Pharmacokinetics of Refametinib
NaSingle-groupOpen-label
Summary
The purpose of this study is to see if there is a difference between the way your body absorbs and distributes BAY86-9766 when given alone or in combination with ketoconazole, a drug which may affect how much BAY86-9766 is absorbed, distributed or eliminated from the body
Timeline
- Start
- 2013-09
- Primary completion
- 2013-12
- Completion
- 2013-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketoconazole | Small molecule | 400 mg | — |
| Subject | Refametinib | Small molecule | 10 mg | — |
| Subject | Refametinib | Small molecule | 20 mg | — |
| Subject | Refametinib | Small molecule | 30 mg | — |
Indications
No indication recorded.