Reduced Nicotine Content Cigarettes in Smokers of Lower Socioeconomic Status

Summary

The overall goal of this study is to address the question of whether progressively lowering nicotine content in cigarettes can reduce or eliminate nicotine dependence in smokers of low socioeconomic status

Timeline

Start

2015-09-09

Primary completion

2018-01-05

Completion

2018-02-23

Outcome

Missed primary endpoint

registry analysis (other test); Reduced Nicotine Content Cigarettes vs Same Nicotine Content Cigarettes; p <0.0001; Hazard Ratio (HR) 3.3 (95% CI 1.95 to 5.58); Regression, Cox NCT01928719 ↗

Publications

• Krebs NM, Allen SI, Veldheer S, Martinez DJ, Horn K, Livelsberger C, Modesto J, Kuprewicz R, Wilhelm A, Hrabovsky S, Kazi A, Fazzi A, Liao J, Zhu J, Wasserman E, Reilly SM, Reinhart L, Trushin N, Moyer RE, Bascom R, Foulds J, Richie JP Jr, Muscat JE. Reduced nicotine content cigarettes in smokers of low socioeconomic status: study protocol for a randomized control trial. Trials. 2017 Jul 3;18(1):300. doi: 10.1186/s13063-017-2038-9.

Drugs

Indications