drugset / Trial / NCT01932385

Sorafenib in Liver Function Impaired Advanced Hepatocellular Carcinoma

NCT01932385

Phase 2/3 Completed 86 enrolled Qingdao Central Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

Due to the HBV and HCV infection, about 55% hepatocellular carcinoma patients happened in China. Among them, only 10% patients can be diagnosed in early stage. Sorafenib increased PFS and OS in advanced hepatocellular carcinoma patients with liver function of Child-Pugh class A patients, but the result for Child-Pugh class B patients is unclear.

Timeline

Start
2013-08-01
Primary completion
2016-01-30
Completion
2016-07-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Sorafenib Small molecule 400 mg Oral

Indications