drugset / Trial / NCT01932385
Sorafenib in Liver Function Impaired Advanced Hepatocellular Carcinoma
RandomizedParallel-groupOpen-labelTreatment
Summary
Due to the HBV and HCV infection, about 55% hepatocellular carcinoma patients happened in China. Among them, only 10% patients can be diagnosed in early stage. Sorafenib increased PFS and OS in advanced hepatocellular carcinoma patients with liver function of Child-Pugh class A patients, but the result for Child-Pugh class B patients is unclear.
Timeline
- Start
- 2013-08-01
- Primary completion
- 2016-01-30
- Completion
- 2016-07-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Sorafenib | Small molecule | 400 mg | Oral |