Impact of Emotional Mimicry and Oxytocin on Frontotemporal Dementia

NCT01937013 ↗

Phase 2 Completed 52 enrolled London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's Canadian Institutes of Health Research (CIHR) · collab

RandomizedCrossoverQuadruple-blindTreatment

Summary

This study will evaluate the effects on emotions and neural activity of a one time dose of intranasal oxytocin vs. placebo in patients with FTD and healthy controls.

Timeline

Start: 2013-09-12
Primary completion: 2017-12-21
Completion: 2017-12-21

Publications

Oliver LD, Stewart C, Coleman K, Kryklywy JH, Bartha R, Mitchell DGV, Finger EC. Neural effects of oxytocin and mimicry in frontotemporal dementia: A randomized crossover study. Neurology. 2020 Nov 10;95(19):e2635-e2647. doi: 10.1212/WNL.0000000000010933. Epub 2020 Sep 22.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Oxytocin	Peptide	72 iu	Intranasal

Impact of Emotional Mimicry and Oxytocin on Frontotemporal Dementia

Summary

Timeline

Publications

Drugs

Indications