drugset / Trial / NCT01938716

Gemcitabine Pharmacokinetics After Preoperative Chemoradiation Therapy

NCT01938716

Terminated 12 enrolled M.D. Anderson Cancer Center
NaSingle-groupOpen-labelBasic science

Summary

The goal of this clinical research study is to learn if gemcitabine given during surgery can enter pancreas cancer cells in patients who have already received chemotherapy and radiation. Gemcitabine is a drug used to treat pancreatic cancer. However, it has not previously been studied if gemcitabine can enter pancreatic cancer cells. Gemcitabine is designed to block the growth of cancer cells, which may cause cancer cells to die.

Timeline

Start
2012-03
Primary completion
2019-06-03
Completion
2019-06-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemcitabine Small molecule 500 mg/m2 Intravenous
Subject Gemcitabine Small molecule 750 mg/m2 Intravenous