drugset / Trial / NCT01940510

A Study of the Effect of Multiple Doses of Rifampin on the Single Dose Pharmacokinetics of RO5424802

NCT01940510

Phase 1 Completed 24 enrolled Hoffmann-La Roche
Non-randomizedSingle-groupOpen-label

Summary

This single center, open-label, 3-period, fixed-sequence study will evaluate the effect of multiple oral doses of rifampin on the pharmacokinetics of a single oral dose of RO5424802 in healthy volunteers. Subjects will receive a single dose of RO5424802 on Days 1 and 17 and rifampin daily from Days 8 to Day 20.

Timeline

Start
2013-10
Primary completion
2013-10
Completion
2013-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Alectinib Small molecule Oral
Subject Rifampin Small molecule Oral

Indications

No indication recorded.