drugset / Trial / NCT01941888
Propofol TCI Administered by Gastroenterologists During Endoscopy: a Randomized Double Blind Controlled Study
RandomizedParallel-groupDouble-blindTreatment
Summary
Many studies address safety and effectiveness of non-anesthesiologist propofol sedation (NAPS) for GI endoscopy. Target Controlled Infusion (TCI) is a sophisticated tool for providing optimal sedation regimen and avoiding under or oversedation. This randomized double blind controlled study compares standard moderate sedation level of sedation (group S) during upper endoscopy (EGD) and colonoscopy (CS) versus propofol NAPS (group P).
Timeline
- Start
- 2012-05
- Primary completion
- 2013-03
- Completion
- 2013-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Midazolam | Small molecule | 0.03 mg/kg | — |
| Comparator | Midazolam | Small molecule | 0.04 mg/kg | — |
| Subject | Propofol | Small molecule | 1.2 ug/ml | — |
| Subject | Propofol | Small molecule | 1.6 ug/ml | — |
Indications
No indication recorded.