drugset / Trial / NCT01945801
Sodium-Restricted Diet and Diuretic in the Treatment of Severe Sleep Apnea
RandomizedParallel-groupDouble-blindTreatment
Summary
This study evaluates the intervention of the 1) sodium-restricted diet, or 2) diuretic, or 3) placebo pill in the treatment of obstructive sleep apnea in adults.
Timeline
- Start
- 2013-10
- Primary completion
- 2015-02
- Completion
- 2015-02
Publications
- Fiori CZ, Martinez D, Montanari CC, Lopez P, Camargo R, Sezera L, Goncalves SC, Fuchs FD. Diuretic or sodium-restricted diet for obstructive sleep apnea-a randomized trial. Sleep. 2018 Apr 1;41(4). doi: 10.1093/sleep/zsy016.
- Fiori CZ, Martinez D, Goncalves SC, Montanari CC, Fuchs FD. Effect of diuretics and sodium-restricted diet on sleep apnea severity: study protocol for a randomized controlled trial. Trials. 2015 Apr 25;16:188. doi: 10.1186/s13063-015-0699-9.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Furosemide | Other / unclassified | 20 mg | — |
| Comparator | Spironolactone | Small molecule | 100 mg | — |