drugset / Trial / NCT01946386

A Vasoconstriction Study With LEO 90100

NCT01946386 ↗

Phase 1 Completed 35 enrolled LEO Pharma
RandomizedSingle-groupSingle-blindTreatment

Summary

The purpose of this study is to compare the pharmacodynamic activity of LEO 90100 with Dermovate® cream, Dovobet® ointment, betamethasone dipropionate in LEO90100 vehicle, Synalar® ointment and LEO 90100 vehicle using a human skin blanching test.

Timeline

Start
2013-09
Primary completion
2013-10
Completion
2013-10

Publications

  • Results Queille-Roussel C, Bang B, Clonier F, Lacour JP. Phase I evaluation of the vasoconstrictor potential of an innovative fixed combination calcipotriene plus betamethasone dipropionate aerosol foam versus other corticosteroid psoriasis treatments. J Am Acad Dermatol. 2015:72 Suppl 1;AB243 (P915).

Drugs

EvaluationDrugModalityDoseRoute
Subject Daivobet Unknown — Topical
Subject LEO 90100 Unknown — Topical
Subject betamethasone dipropionate Small molecule — Topical
Subject clobetasol propionate Small molecule — Topical
Subject fluocinolone acetonide Other / unclassified — Topical

Indications