drugset / Trial / NCT01946386
A Vasoconstriction Study With LEO 90100
RandomizedSingle-groupSingle-blindTreatment
Summary
The purpose of this study is to compare the pharmacodynamic activity of LEO 90100 with Dermovate® cream, Dovobet® ointment, betamethasone dipropionate in LEO90100 vehicle, Synalar® ointment and LEO 90100 vehicle using a human skin blanching test.
Timeline
- Start
- 2013-09
- Primary completion
- 2013-10
- Completion
- 2013-10
Publications
- Results Queille-Roussel C, Bang B, Clonier F, Lacour JP. Phase I evaluation of the vasoconstrictor potential of an innovative fixed combination calcipotriene plus betamethasone dipropionate aerosol foam versus other corticosteroid psoriasis treatments. J Am Acad Dermatol. 2015:72 Suppl 1;AB243 (P915).
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Daivobet | Unknown | — | Topical |
| Subject | LEO 90100 | Unknown | — | Topical |
| Subject | betamethasone dipropionate | Small molecule | — | Topical |
| Subject | clobetasol propionate | Small molecule | — | Topical |
| Subject | fluocinolone acetonide | Small molecule | — | Topical |