Ubiquinol (Reduced COQ10) for Patients With Sepsis

Summary

This study aims to determine if Ubiquinol (reduced form of COQ10) will attenuate mitochondrial injury and decrease inflammatory response in patients suffering from sepsis.

Timeline

Start

2012-10

Primary completion

2014-04

Completion

2014-04

Publications

• Donnino MW, Mortensen SJ, Andersen LW, Chase M, Berg KM, Balkema J, Radhakrishnan J, Gazmuri RJ, Liu X, Cocchi MN. Ubiquinol (reduced Coenzyme Q10) in patients with severe sepsis or septic shock: a randomized, double-blind, placebo-controlled, pilot trial. Crit Care. 2015 Jul 1;19(1):275. doi: 10.1186/s13054-015-0989-3.

Drugs

Indications