drugset / Trial / NCT01949532

Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Multiple Myeloma and Renal Disease

NCT01949532

Phase 1 Completed 26 enrolled Amgen
Non-randomizedParallel-groupOpen-labelOther

Summary

The purpose of this study is to see how the body and the cancer react to carfilzomib, including measuring the amount of the study drug in the blood at certain times following dosing. This study is being done in people with normal kidney function and those with end-stage renal disease to see if they respond differently to the study drug.

Timeline

Start
2014-01
Primary completion
2015-04
Completion
2017-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Carfilzomib Other / unclassified 56 mg/m2 Intravenous