drugset / Trial / NCT01952223

A Phase III of Cabazitaxel and Pelvic Radiotherapy in Localized Prostate Cancer and High-risk Features of Relapse

NCT01952223

Phase 3 Active not recruiting 761 enrolled UNICANCER Sanofi · collab
RandomizedFactorialOpen-labelTreatment

Summary

The objective of this study is to assess the effect of neoadjuvant cabazitaxel and pelvic radiotherapy in combination with androgen deprivation therapy (ADT)-radiotherapy on clinical progression-free survival in patients with high-risk localized prostate cancer (with a stringent selection of patients with at least 2 high-risk features), in a 2 by 2 factorial trial.

Timeline

Start
2013-12
Primary completion
2025-12
Completion
2041-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Cabazitaxel Other / unclassified 25 mg/m2 Intravenous