drugset / Trial / NCT01952769
Anti PD1 Antibody in Diffuse Intrinsic Pontine Glioma
NaSingle-groupOpen-labelTreatment
Summary
Diffuse pontine gliomas are incurable with currently used treatments. based on data stating that progressive tumors inhibit immune system, would try to enhance immune system activity and tumor cell killing. anti PD1 prevents one of the important mechanisms allowing the tumor to supress the immune system thus we hope it will allow for prolonged control of the tumors
Timeline
- Start
- 2014-02
- Primary completion
- 2018-11
- Completion
- 2019-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pidilizumab | Monoclonal antibody | 1 mg/kg | Intravenous |
| Subject | Pidilizumab | Monoclonal antibody | 6 mg/kg | Intravenous |