A Study to Investigate Evoked Potentials as Markers of Ketamine-induced Cortical Plasticity in Patients With Major Depressive Disorder

Summary

To evaluate if somatosensory evoked potentials (SEPs) and motor evoked potentials (MEPs) obtained with electroencephalography (EEG) and electromyography (EMG) can be used to detect changes in cortical plasticity in responders to a single IV infusion of ketamine as compared to non-responders.

Timeline

Start

2014-02

Primary completion

2015-09

Completion

2015-09

Outcome

Outcome not reported

Stopped: “Clinical Team decision to terminate the study after the results from Cohort 1 did not support conducting Cohort 2.”

Drugs

Indications