drugset / Trial / NCT01957956
Vaccine Therapy and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma
NaSingle-groupOpen-labelTreatment
Summary
This pilot clinical trial studies vaccine therapy and temozolomide in treating patients with newly diagnosed glioblastoma. Vaccines made from a person's white blood cells mixed with tumor proteins may help the body build an effective immune response to kill tumor cells. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving vaccine therapy and temozolomide may be an effective treatment for glioblastoma.
Timeline
- Start
- 2013-11-11
- Primary completion
- 2016-11-16
- Completion
- 2016-11-16
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Malignant Glioma Tumor Lysate-Pulsed Autologous Dendritic Cell Vaccine | Vaccine | — | Intramuscular |
| Subject | Temozolomide | Small molecule | — | Oral |